BDBM86053 B-HT 920::CAS_101626-70-4::CHEMBL279085::NSC_104870::Talipexole::cid_5374

SMILES Nc1nc2CCN(CC=C)CCc2s1

InChI Key InChIKey=DHSSDEDRBUKTQY-UHFFFAOYSA-N

Data  29 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 86053   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM86053(B-HT 920 | CAS_101626-70-4 | CHEMBL279085 | NSC_10...)
Affinity DataKi:  5.80nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the agonist [3H]quinpirole to label the high affinity state (D2 h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM86053(B-HT 920 | CAS_101626-70-4 | CHEMBL279085 | NSC_10...)
Affinity DataKi:  617nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM86053(B-HT 920 | CAS_101626-70-4 | CHEMBL279085 | NSC_10...)
Affinity DataKi:  977nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM86053(B-HT 920 | CAS_101626-70-4 | CHEMBL279085 | NSC_10...)
Affinity DataKi:  2.70E+3nMAssay Description:In vitro binding affinity to rat striatal Dopamine receptor D2 was determined using the antagonist [3H]spiperone + GTP to label the low affinity stat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed